Anti-Semaphorin 4D Antibody [A8] (A248145)

Mouse monoclonal [A8] antibody to Semaphorin 4D for Functional Studies, Flow Cytometry and IF.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-Semaphorin 4D Antibody [A8]
Description
Mouse monoclonal [A8] antibody to Semaphorin 4D.
Specificity
This antibody recognizes a homodimeric protein comprised of 50kDa subunits, identified as CD100. It is expressed on majority of haemopoietic cells (B, T, NK and myeloid cells) and is absent from bone marrow, erythrocytes, eosinophils and endothelial cells. Its expression is increased after PHA-activation. CD100 was shown to associate with different partner molecules in T cells such as CD45, a key molecule with protein tyrosine phosphatase activity involved in T-cell transduction, and a Serine kinase. It plays a role in homotypic cell adhesion and in T cell activation.
Applications
Functional Studies, Flow Cytometry, IF
Dilutions
Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml
Reactivity
Human, Monkey, Mouse
Immunogen
PHA stimulated human peripheral blood lymphocytes.
Host
Mouse
Clonality
Monoclonal
Clone ID
A8
Isotype
IgG1
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
50 kDa (monomer)
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-Semaphorin 4D Antibody [A8] - BSA and Azide free (A251328).
Synonyms
A8, BB 18, BB18, CD 100, CD100, CD100 antigen, Coll 4, COLL4, Collapsin 4, Collapsin4, GR3, Leukocyte activation antigen CD100, M sema G, MSEMA, SEM4D_HUMAN, Sema 4d, Sema domain immunoglobulin domain Ig transmembrane domain TM and short cytoplasmic domain semaphorin 4D, Sema H, SEMA J, Sema4d, Semacl 2, Semacl2, SemaH, SEMAJ, Semaphorin C like 2, Semaphorin H, Semaphorin J, Semaphorin-4D, Semaphorin4D, SemaphorinJ, Semcl 2, Semcl2
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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