Anti-Serum Amyloid P Antibody [APCS/3240] (A248870)

Mouse monoclonal [APCS/3240] antibody to Serum Amyloid P for IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-Serum Amyloid P Antibody [APCS/3240]
Description
Mouse monoclonal [APCS/3240] antibody to Serum Amyloid P.
Specificity
Serum amyloid P (SAP) is a glycoprotein belonging to the pentraxin family of proteins, which has a characteristic pentameric organization and calciumdependent ligand binding. Secreted by liver epithelial cells, SAP is found in serum and urine. Although the function of SAP has not been clearly established, it has been shown to interact with DNA and histones and is thought to play a role in scavenging nuclear material released from damaged circulating cells. Also designated PTX2, SAP is a precursor of the protein amyloid P component (AP), which is universally associated with the amyloid deposits in all forms of amyloidoses, including Alzheimer s disease. SAP is a decamer of ten identical, noncovalently linked subunits, each of which may be post-translationally modified by glycosylation.
Applications
IHC-P
Dilutions
IHC-P: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant fragment, around amino acids 143-223, of human APCS protein. The exact sequence is proprietary.
Host
Mouse
Clonality
Monoclonal
Clone ID
APCS/3240
Isotype
IgG2b
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
200 kDa (oligomeric) / 26 kDa (non-covalently bound subunit) / 30 kDa (glycosylated SAP subunit)
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-Serum Amyloid P Antibody [APCS/3240] - BSA and Azide free (A252050).
Synonyms
9.5S alpha 1 glycoprotein, 9.5S alpha-1-glycoprotein, Amyloid P component serum, APCS, MGC88159, Pentaxin related, Pentraxin 2, PTX 2, PTX2, SAMP_HUMAN, SAP, Serum amyloid P component, Serum amyloid P-component(1-203)
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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