Anti-SOX4 Antibody [PCRP-SOX4-1D6] - BSA and Azide free (A278384)

Mouse monoclonal [PCRP-SOX4-1D6] antibody to SOX4 for IP, Flow Cytometry, IF, WB and IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-SOX4 Antibody [PCRP-SOX4-1D6] - BSA and Azide free
Description
Mouse monoclonal [PCRP-SOX4-1D6] antibody to SOX4.
Specificity
SOX4 is a member of the SOX (SRY-related HMG-box) family of transcription factors with a critical role in embryonic development and in cell-fate determination during organogenesis of the heart, pancreas, brain, and in B and T lymphocyte differentiation. SOX4 gene expression is upregulated in many cancer types, and increased SOX4 activity contributes to cellular transformation, cell survival, and metastasis. Gene expression profiling has uncovered SOX4 with upregulated activity during TGF-β-induced epithelial-mesenchymal transition (EMT) in normal and cancerous breast epithelial cells. SOX4 is indispensable for EMT and cell survival invitro and for primary tumor growth and metastasis invivo. SOX4 is identified as a master regulator of EMT by governing the expression of the epigenetic modifier Ezh2.
Applications
IP, Flow Cytometry, IF, WB, IHC-P
Dilutions
IP: 1-2µg / 100-500µg proteins, Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, WB: 1-2 µg/ml, IHC-P: 1-2 µg/ml
Reactivity
Human
Cross Reactivity
This antibody is predicted to cross react with Xenopus and Chicken.
Immunogen
Recombinant fragment, around amino acids 45-130, of human SOX4 protein. The exact sequence is proprietary.
Host
Mouse
Clonality
Monoclonal
Clone ID
PCRP-SOX4-1D6
Isotype
IgG2b
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Molecular Weight
47 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-SOX4 Antibody [PCRP-SOX4-1D6] (A277796).
Synonyms
Ecotropic viral integration site 16, EVI 16, EVI16, SOX4_HUMAN, SRY (sex determining region Y) box 4, SRY box containing gene 4, SRY related HMG box gene 4, Transcription factor SOX-4
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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