Anti-StAR Antibody [STAR/3976] - BSA and Azide free (A317058)

$765

Mouse monoclonal [STAR/3976] antibody to StAR for IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-StAR Antibody [STAR/3976] - BSA and Azide free
Description
Mouse monoclonal [STAR/3976] antibody to StAR.
Specificity
Steroidogenic Acute Regulatory Protein (STAR) controls the rate-limiting step of steroidegenesis by translocating cholesterol from the outer mitochondrial membrane to the inner membrane where it is later cleaved to pregnenolone.It is primarily present in steroid-producing cells, including Leydig cells in the testis, theca cells and luteal cells in the ovary and adrenal cells in the adrenal cortex. Due to low levels of pregnenolone, seminomas and Leydig cell tumors display no specific STAR staining. Therefore, STAR antibody may assist in differentiating sex cord stromal tumors (SCST), seminomas and embryonal carcinomas.
Applications
IHC-P
Positive Control
K-562 cells. Human adrenal or testicular carcinoma.
Dilutions
IHC: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant fragment (around Amino Acids 39-108) of human STAR protein. The exact sequence is proprietary.
Host
Mouse
Clonality
Monoclonal
Clone ID
STAR/3976
Isotype
IgG1
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Molecular Weight
30 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonyms
Cholesterol trafficker, Luteinizing hormone induced protein, mitochondrial, Mitochondrial steroid acute regulatory protein, StAR related lipid transfer (START) domain containing 1, StARD1, START domain containing 1, START domain containing protein 1, START domain-containing protein 1, STAR_HUMAN, Steroid acute regulatory protein, Steroidogenic acute regulator, Steroidogenic acute regulatory protein, Steroidogenic acute regulatory protein mitochondrial
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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