Anti-Synaptotagmin 1 Antibody (FITC)
Rabbit polyclonal antibody to Synaptotagmin 1 (FITC) from FabGennix (SYT1-FITC).
|Name:||Anti-Synaptotagmin 1 Antibody (FITC)|
|Description:||Rabbit polyclonal antibody to Synaptotagmin 1 (FITC)|
|Dilutions:||DB: 1:10,000; ELISA: 1:10,000; Western Blot: 1:500|
|Reactivity:||Human, Mouse, Rat|
|Immunogen:||Synthetic peptide taken within amino acid region 1-60 on SYT1 protein.|
|Concentration:||0.64-0.72 µg/µl in antibody stabilization buffer|
|Storage:||-20⁰C for long term storage|
|Function:||May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-independent manner; these are neurexins, syntaxin and AP2. Plays a role in dendrite formation by melanocytes (PubMed:23999003).|
|Tissue Specificity:||Expressed in melanocytes (PubMed:23999003).|
|Sequence Similarities:||Belongs to the synaptotagmin family.|
|Cellular Location:||Cytoplasmic vesicle > Secretory vesicle membrane. Cytoplasmic vesicle > Secretory vesicle > Synaptic vesicle membrane. Cytoplasmic vesicle > Secretory vesicle > Chromaffin granule membrane. Cytoplasm.
Synaptic vesicles and chromaffin granules.
Synaptotagmin 2 Antibody
Synaptotagmin I Antibody
Synaptotagmin II Antibody
|Information:||Target information shown above is from the UniProt Consortium.|
Please Note: Anti-Synaptotagmin 1 Antibody (FITC) is for research use only. It is not intended for diagnostic of therapeutic use.