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Anti-Synaptotagmin 1 Antibody (FITC)

 
Rabbit polyclonal antibody to Synaptotagmin 1 (FITC) from FabGennix (SYT1-FITC).
Overview
Name: Anti-Synaptotagmin 1 Antibody (FITC)
Description: Rabbit polyclonal antibody to Synaptotagmin 1 (FITC)
Applications: ELISA, WB
Dilutions: DB: 1:10,000; ELISA: 1:10,000; Western Blot: 1:500
Reactivity: Human, Mouse, Rat
Immunogen: Synthetic  peptide taken within amino acid region 1-60 on SYT1 protein.
Host: Rabbit
Clonality: Polyclonal
Conjugate: FITC
Concentration: 0.64-0.72 µg/µl in antibody stabilization buffer
Storage: -20⁰C for long term storage

Target
Function: May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-independent manner; these are neurexins, syntaxin and AP2. Plays a role in dendrite formation by melanocytes (PubMed:23999003).
Tissue Specificity: Expressed in melanocytes (PubMed:23999003).
Sequence Similarities: Belongs to the synaptotagmin family.
Cellular Location: Cytoplasmic vesicle > Secretory vesicle membrane. Cytoplasmic vesicle > Secretory vesicle > Synaptic vesicle membrane. Cytoplasmic vesicle > Secretory vesicle > Chromaffin granule membrane. Cytoplasm.

Synaptic vesicles and chromaffin granules.
UniProt: P21579
Synonyms: DKFZp781D2042 Antibody
FLJ42519 Antibody
p65 Antibody
SVP65 Antibody
Synaptotagmin 2 Antibody
Synaptotagmin I Antibody
Synaptotagmin II Antibody
Synaptotagmin-1 Antibody
SYT Antibody
Syt1 Antibody
SYT1_HUMAN Antibody
Syt2 Antibody
SytI Antibody
Information: Target information shown above is from the UniProt Consortium.


Please Note: Anti-Synaptotagmin 1 Antibody (FITC) is for research use only. It is not intended for diagnostic of therapeutic use.
Antibodies.com | SYT1-FITC
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100µg £429

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