Synthetic Nanodisc Human CCR4 Protein (A318474)

Name: Synthetic Nanodisc Human CCR4 Protein
Brand: Antibodies.com
SKU: A318474
Price: 1300.0 USD
Availability: InStock

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$1,300

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$40 to United States

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7-8 Business Days

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Specifications

Name

Synthetic Nanodisc Human CCR4 Protein

Description

Synthetic nanodiscs offer a stable and biologically relevant environment that closely mimics cell membranes and enables full-length transmembrane human CCR4 protein to be purified and analysed in vitro.

Applications

ELISA, SDS-PAGE

Expression System

HEK293 cells

Nature

Synthetic

Protein Species

Human

Protein Length

Full length protein.

Molecular Weight

Full length human CCR4 protein has a MW of 41.4 kDa.

Conjugate

Unconjugated

Product Form

Lyophilized

Concentration

Reconstitution dependent.

Formulation

Lyophilized from nanodisc solubilization buffer (20mM Tris-HCl, 150mM NaCl, pH 8.0). Normally 5%–8% Trehalose is added as a protectant before lyophilization.

Storage

Shipped at 4°C. Lyophilized: Store at -20°C to -80°C. Reconstituted: Aliquot and store at -80°C. Product is stable for one year. Avoid freeze/thaw cycles.

Synonyms

C C chemokine receptor type 4, C C CKR 4, C-C chemokine receptor type 4, C-C CKR-4, CC CKR 4, CC-CKR-4, CCR 4, CCR-4, CCR4_HUMAN, CD194, Chemokine (CC motif) receptor 4, chemokine C C motif receptor 4, ChemR13, CKR4, CMKBR 4, CMKBR4, HGCN 14099, K5 5, K5-5, MGC88293

Disclaimer

This product is for research use only. It is not intended for diagnostic or therapeutic use.

Scientific Validation Data (3)

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Figure 1: Synthetic Nanodisc Human CCR4 Protein (A318474)

ELISA plates were pre-coated with Synthetic Nanodisc Human CCR4 Protein (A318474) (0.2 µg/well). Serial diluted Anti-CCR4 Humanized Antibody [Mogamulizumab Biosimilar] - Azide free (A318876) solutions were added, washed, and incubated with secondary antibody before ELISA reading. From this data, the EC50 for Anti-CCR4 Monoclonal Antibody binding with CCR4-Nanodisc is 40.3 µg/ml.

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Figure 2: SDS-PAGE - Synthetic Nanodisc Human CCR4 Protein (A318474)

Synthetic Nanodisc Human CCR4 Protein (A318474) on SDS-PAGE under reducing conditions.

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Figure 3: Synthetic Nanodisc Human CCR4 Protein (A318474)

Diagram showing how synthetic nanodiscs containing full-length multi-pass transmembrane proteins in a phospholipid bilayer are generated from native cell membranes.

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