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Anti-TGF beta Antibody

Mouse monoclonal (2C5) antibody to Transforming Growth Factor beta from Anogen (MO-C40009B).

   Please Note: This is exactly the same antibody that is marketed as:


 
   •  Abcam | ab18679
Name: Anti-TGF beta Antibody
Description: Mouse monoclonal (2C5) antibody to Transforming Growth Factor beta.
Specificity: Western blotting demonstrated that this antibody reacts with the dimeric (25 kDa) and monomeric (12.5 kDa) forms of TGF-b under both non-reducing and reducing conditions respectively. This antibody recognises both human platelet-derived and recombinant TGF-b in ELISA.
Applications: ELISA, WB
Reactivity: Human
Immunogen: TGF-β from human platelets.
Host: Mouse
Clonality: Monoclonal
Clone: 2C5
Myeloma: Sp2/0-Ag14
Isotype: IgG1
Conjugate: Unconjugated
Concentration: Reconstitution dependent.
Purity: Protein G affinity chromatagraphy.
Product Form: Lyophilised
Reconstitution: Reconstitute with double distilled water.
Formulation: Lyophilised from a solution of 0.01M Phosphate Buffered Saline, pH 7.0.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Introduction: Transforming growth factor beta (TGF-β) has three isoforms (TGF-β1, TGF-β2, and TGF-β3) with similar functions. The cytokine is a homodimer linked by disulfide bind. Inside cells, the cytokine forms a small latent complex with latent associated peptide (LAP). This small complex binds to latent TGF-β binding protein (LTBP) to be secreted to extra-cellular matrix. Disassociation of the latent proteins from TGF-β results in the release of the cytokine to its receptor. The process is called activation, which can be influenced by various factors, including proteases, metalloproteases, extreme pH, mild acidic condition, reactive oxygen species and integrins. TGF-β is an anti-proliferation factor in normal cells. It increases the synthesis of p15 and p21, which can block the cyclin: CDK complex, and causes cells to stop at G1 phase. The cytokine can induce apoptosis through both SMAD and DAXX pathways. In cancer cells, TGF-β signaling is altered and TGF-β no longer stops cell proliferation.
Synonyms: Activin receptor type II Antibody
Atr Antibody
CED Antibody
DPD1 Antibody
LAP Antibody
Latency-associated peptide Antibody
Prepro transforming growth factor beta 1 Antibody
Pun Antibody
Punt Antibody
Put Antibody
STKC Antibody
TGF B Antibody
TGF beta 1 Antibody
TGF beta 1 protein Antibody
TGF-beta 1 protein Antibody
TGF-beta-1 Antibody
TGF-beta-5 Antibody
TGF-beta1 Antibody
TGFB Antibody
Tgfb-1 Antibody
tgfb1 Antibody
TGFB1_HUMAN Antibody
TGFbeta Antibody
TGFbeta1 Antibody
Transforming Growth Factor b1 Antibody
Transforming Growth Factor beta 1 Antibody
Transforming growth factor beta 1a Antibody
transforming growth factor beta-1 Antibody
transforming growth factor, beta 1 Antibody
Western blot analysis of TGF-beta using Anti-TGF beta Antibody. The blot was stained with HRP substrate 4-Chloro-1- naphthol and H2O2.
Please Note: All batches are extensively validated and are guaranteed to work as specified, however, QC data is not necessarily from the current lot on sale.
Total Citations (3)
Description: Mouse monoclonal (TB21) antibody to Transforming Growth Factor beta.
Application: IHC, WB
Host: Mouse
Isotype: IgG1
Reactivity: Human

£239 – £342

Description: Mouse monoclonal (2C6) antibody to Transforming Growth Factor beta.
Application: WB, IHC
Host: Mouse
Isotype: IgG1
Reactivity: Human

£239 – £342

Description: Mouse monoclonal (2E6) antibody to Transforming Growth Factor beta.
Application: ELISA, WB
Host: Mouse
Isotype: IgG1
Reactivity: Human

£239 – £342

Description: Mouse monoclonal (8C4) antibody to Transforming Growth Factor beta.
Application: ELISA, IHC
Host: Mouse
Isotype: IgG1
Reactivity: Human

£239 – £342

Please Note: Anti-TGF beta Antibody is for research use only. It is not intended for diagnostic or therapeutic use.
Antibodies.com | MO-C40009B
Size Price Quantity
100µg £239
500µl £342

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Lead Time: Currently 4-6 Days
Shipping Information
  • £20 to United Kingdom
  • £35 to Europe