Anti-Thyroglobulin Antibody [56.7D7] (A279404)

Anti-Thyroglobulin Antibody [56.7D7]

Mouse monoclonal [56.7D7] antibody to Thyroglobulin.

This antibody recognises human thyroglobulin, a ~660 kDa homodimer produced by the thyroid gland, specifically in the thyrocytes, and stored within the follicular lumen. Thyroglobulin is the precursor of the iodated thyroid hormones thyroxine (T4) and triiodothyronine (T3). These hormones affect protein, fat and carbohydrate metabolism. Defects in thyroglobulin production can lead to goiter, and increased susceptibility to autoimmune thyroid type 3 diseases, such as Graves disease and Hashimoto thyroiditis. Mouse anti Human Tg, Clone 56.7D7 shows negligible cross reactivity (<0.01% ) with human serum albumin, human immunoglobulin, T3 and T4.

ELISA: 1:10,000 - 1:100,000

Human

Mouse

Monoclonal

56.7D7

IgG1

Unconjugated

1 mg/ml

Liquid

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Mouse anti Human Tg, Clone 56.7D7 recognizes human thyroglobulin, a ~660 kDa homodimer produced by the thyroid gland, specifically in the thyrocytes, and stored within the follicular lumen. Thyroglobulin is the precursor of the iodated thyroid hormones thyroxine (T4) and triiodothyronine (T3). These hormones affect protein, fat and carbohydrate metabolism. Defects in thyroglobulin production can lead to goiter, and increased susceptibility to autoimmune thyroid type 3 diseases, such as Graves disease and Hashimoto thyroiditis. Mouse anti Human Tg, Clone 56.7D7 shows negligible cross reactivity (<0.01%) with human serum albumin, human immunoglobulin, T3 and T4.

AITD 3, AITD3, hTG, TDH3, Tg, TGN, THYG_HUMAN