Recombinant Anti-TL1A Antibody [VEGI/7799R] - BSA and Azide free (A317118)

$765

Recombinant rabbit monoclonal [VEGI/7799R] antibody to TL1A for IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-TL1A Antibody [VEGI/7799R] - BSA and Azide free
Description
Recombinant rabbit monoclonal [VEGI/7799R] antibody to TL1A.
Specificity
VEGI is an anti-angiogenic cytokine that belongs to tumor necrosis factor superfamily, member 15 (TNFSF15). This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. Reduced expression of VEGI has been reported as a marker of poor prognosis in breast cancer.
Applications
IHC-P
Positive Control
Endothelial cells. Colon, intestine, placenta, lung or prostate.
Dilutions
IHC: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant full-length human VEGI protein.
Host
Rabbit
Clonality
Monoclonal
Clone ID
VEGI/7799R
Isotype
IgG
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A chromatography.
Concentration
1 mg/ml
Molecular Weight
22 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonyms
MGC129934, MGC129935, tl1, TL1 A, tnf ligand related molecule 1, TNF ligand-related molecule 1, tnf superfamily ligand tl1a, TNF15_HUMAN, TNFSF15, Tumor necrosis factor (ligand) superfamily member 15, Tumor necrosis factor ligand superfamily member 15, Tumor necrosis factor ligand superfamily member 15, secreted form, Vascular endothelial cell growth inhibitor, Vascular endothelial growth inhibitor, Vascular endothelial growth inhibitor 192a, vegi, VEGI192A
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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