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Anti-TMEM16A Antibody (Biotin)

Rabbit polyclonal antibody to TMEM16A (Biotin) from FabGennix (TMEM16.112-BIOTIN).
Name: Anti-TMEM16A Antibody (Biotin)
Description: Rabbit polyclonal antibody to TMEM16A (Biotin)
Applications: ELISA, IMM, WB
Dilutions: DB: 1:10,000; ELISA: 1:10,000; Immunoprecipitation: 1:200; Western Blot: 1:500
Reactivity: Human
Immunogen: Synthetic peptide taken within amino acid region 900-950 on human Transmembrane protein 16A.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Biotin
Concentration: 0 .50 µg/µl in antibody stabilization buffer
Storage: -20⁰C for long term storage
Function: Calcium-activated chloride channel (CaCC) which plays a role in transepithelial anion transport and smooth muscle contraction. Required for the normal functioning of the interstitial cells of Cajal (ICCs) which generate electrical pacemaker activity in gastrointestinal smooth muscles. Acts as a major contributor to basal and stimulated chloride conductance in airway epithelial cells and plays an important role in tracheal cartilage development.
Tissue Specificity: Broadly expressed with higher levels in liver, skeletal muscle and gastrointestinal muscles.
Sequence Similarities: Belongs to the anoctamin family.
Cellular Location: Cell membrane. Cytoplasm.

Cytoplasmic localization seen in neoplastic cells of head and neck squamous cell carcinoma (HNSCC) tumors.
UniProt: Q5XXA6
Synonyms: ANO 1 Antibody
ANO1 Antibody
ANO1_HUMAN Antibody
Anoctamin 1 Antibody
Anoctamin 1 calcium activated chloride channel Antibody
Anoctamin-1 Antibody
Anoctamin1 Antibody
Ca2+ activated Cl- channel Antibody
Calcium Activated Chloride Channel Antibody
Discovered on gastrointestinal stromal tumors protein 1 Antibody
DOG 1 Antibody
FLJ10261 Antibody
Membrane protein Antibody
Oral cancer overexpressed 2 Antibody
Oral cancer overexpressed protein 2 Antibody
ORAOV 2 Antibody
ORAOV2 Antibody
TAOS 2 Antibody
TAOS2 Antibody
TMEM 16A Antibody
Transmembrane protein 16A Antibody
Transmembrane protein 16A (eight membrane spanning domains) Antibody
Tumor amplified and overexpressed sequence 2 Antibody
Tumor-amplified and overexpressed sequence 2 Antibody
Information: Target information shown above is from the UniProt Consortium.
Description: Rabbit polyclonal antibody to TMEM16A (Biotin)
Application: ELISA, IHC, IP, WB
Host: Rabbit
Reactivity: Monkey, Mouse, Rat
Immunogen: Synthetic peptide taken within amino acid region on 70-120 on mouse Transmembrane Protein 16A.


Please Note: Anti-TMEM16A Antibody (Biotin) is for research use only. It is not intended for diagnostic or therapeutic use.
Antibodies.com | TMEM16.112-BIOTIN
Size Price Quantity
100µg £429

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