Anti-Tryptophan Hydroxylase / TPH Antibody (A283963)

Anti-Tryptophan Hydroxylase / TPH Antibody

Sheep polyclonal antibody to Tryptophan Hydroxylase / TPH.

This antibody recognises tryptophan hydroxylase (TPH) which catalyses the 5-hydroxylation of tryptophan, in the first stage of indoleamine biosynthesis. Serotonin biosynthesis occurs principally in neurons which originate in the raphe nucleus of the brain, and melatonin synthesis takes place within the pineal gland.

WB, IHC-Fr

IHC-Fr: 1:1,000, WB: 1:1,000

Human, Rat

This antibody does not cross react with Rabbit

Recombinant rabbit tryptophan hydroxylase purified from E. coli.

Sheep

Polyclonal

IgG

Lot Specific

Approximately 55 kDa in human dorsal Raphe nucleus lysates.

Liquid

Supplied in 10mM HEPES, pH 7.5, with 0.01% BSA, 50% Glycerol, and 0.09% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Sheep anti Human tryptophan hydroxylase antibody recognizes tryptophan hydroxylase (TPH) which catalyses the 5-hydroxylation of tryptophan, in the first stage of indoleamine biosynthesis. Serotonin biosynthesis occurs principally in neurons which originate in the raphe nucleus of the brain, and melatonin synthesis takes place within the pineal gland.