Anti-TTF1 Antibody [8G7G3/1 + NX2.1/690] - BSA and Azide free (A253322)

Name: Anti-TTF1 Antibody [8G7G3/1 + NX2.1/690] - BSA and Azide free
Brand: Antibodies.com
SKU: A253322
Price: 525.0 USD
Availability: InStock

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$525

Mouse monoclonal [8G7G3/1 + NX2.1/690] antibody to TTF1 for Flow Cytometry, IF and IHC-P.

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Alternative Formats and ConjugatesAlternative Formats

Unconjugated

Delivery

Freight Charges

$40 to United States

Lead Time

4-6 Business Days

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Telephone

+1 (314) 370-6046

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Specifications

Name

Anti-TTF1 Antibody [8G7G3/1 + NX2.1/690] - BSA and Azide free

Description

Mouse monoclonal [8G7G3/1 + NX2.1/690] antibody to TTF1.

Specificity

This antibody recognizes a protein of 40kDa, identified as Thyroid transcription factor-1 (TTF-1). TTF-1 is a member of the NKx2 family of homeodomain transcription factors. It is expressed in epithelial cells of the thyroid gland and the lung. Nuclei from liver, stomach, pancreas, small intestine, colon, kidney, breast, skin, testes, pituitary, prostate, and adrenal glands are unreactive. Anti-TTF-1 is useful in differentiating primary adenocarcinoma of the lung from metastatic carcinomas originating in the breast, mediastinal germ cell tumors, and malignant mesothelioma. It can also be used to differentiate small cell lung carcinoma from lymphoid infiltrates.Loss of TTF-1 expression in non-small cell lung carcinoma has been associated with aggressive behavior of such neoplasms. TTF-1 reactivity is also seen in thyroid malignancies.

Applications

Flow Cytometry, IF, IHC-P

Dilutions

Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, IHC-P: 1-2 µg/ml

Reactivity

Human, Mouse, Rat

Immunogen

Clone 8G7G3/1: Recombinant full-length rat TTF-1 protein. Clone NX2.1/690: Recombinant TTF-1 protein.

Host

Mouse

Clonality

Oligoclonal

Clone ID

8G7G3/1 + NX2.1/690

Isotype

IgG1, kappa + IgG1, kappa

Conjugate

Unconjugated

Purification

Protein A/G chromatography.

Concentration

1 mg/ml

Molecular Weight

40 kDa

Product Form

Liquid

Formulation

Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

General Notes

Please note, this product is an oligoclonal antibody; it is a cocktail of monoclonal antibodies that have been carefully selected. Oligoclonal antibodies not only have the specificity and batch-to-batch consistency of a monoclonal antibody, but they also have the advantage of the sensitivity of a polyclonal antibody due to their ability to recognize multiple epitopes on an antigen.

This oligoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-TTF1 Antibody [8G7G3/1 + NX2.1/690] (A250142).

Synonyms

AV026640, BCH, Benign chorea, BHC, Homeobox protein NK 2 homolog A, Homeobox protein NK-2 homolog A, Homeobox protein Nkx 2.1, Homeobox protein Nkx-2.1, Homeobox protein Nkx2.1, NK 2, NK 2 homolog A, NK2, NK2 homeobox 1, NK2, drosophila, homolog of, A, NK2.1, mouse, homolog of, Nkx 2 1, NKX 2.1, NKX 2A, NKX2 1, Nkx2-1, NKX2.1, NKX21_HUMAN, NKX2A, T EBP, T/EBP, TEBP, Thyroid nuclear factor, Thyroid nuclear factor 1, Thyroid specific enhancer binding protein, Thyroid transcription factor 1, Tin man, Tinman, TITF 1, TITF1, TTF 1, TTF-1

Suitable Secondaries

See all Anti-Mouse IgG Secondaries →

Disclaimer

This product is for research use only. It is not intended for diagnostic or therapeutic use.

Scientific Validation Data (2)

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Figure 1: Immunohistochemistry - Anti-TTF1 Antibody [8G7G3/1 + NX2.1/690] - BSA and Azide free (A253322)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded human lung adenocarcinoma using Anti-TTF1 Antibody [8G7G3/1 + NX2.1/690].

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Figure 2: Immunohistochemistry - Anti-TTF1 Antibody [8G7G3/1 + NX2.1/690] - BSA and Azide free (A253322)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded human thyroid using Anti-TTF1 Antibody [8G7G3/1 + NX2.1/690].

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