Anti-UACA Antibody [UACA/1222] - BSA and Azide free
Description
Mouse monoclonal [UACA/1222] antibody to UACA.
Specificity
UACA (Uveal Autoantigen with Coiled-coil domains and Ankyrin repeats) is a 1,416 amino acid nuclear membrane protein. It was originally identified as an autoantigen in patients with panuveitis, a characteristic of Vogt-Koyanagi-Harada disease, and in patients with Graves' disease. UACA was also later identified as Nucling, an mRNA differentially expressed in F9 embryonal carcinoma cells during cardiac muscle differentiation. UACA appears to function as a pro-apoptotic protein that recruits the apaf-1-pro-caspase-9 complex for the induction of apoptosis to mediate the cell-death pathway.
Applications
WB
Dilutions
WB: 1-2 µg/ml
Reactivity
Human, Mouse
Immunogen
Recombinant human UACA protein.
Host
Mouse
Clonality
Monoclonal
Clone ID
UACA/1222
Isotype
IgG1
Light Chains
kappa
Conjugate
Unconjugated
Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Molecular Weight
160 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Figure 1: Western Blot - Anti-UACA Antibody [UACA/1222] - BSA and Azide free (A252873)
Western blot analysis of A549 cell lysate using Anti-UACA Antibody [UACA/1222].
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