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Anti-ULBP1 Antibody

Rabbit polyclonal antibody to ULBP1 from ABclonal (A10483).
Name: Anti-ULBP1 Antibody
Description: Rabbit polyclonal antibody to ULBP1.
Applications: WB
Dilutions: WB: 1:1000 - 1:2000.
Reactivity: Human
Immunogen: Recombinant protein of human ULBP1.
Protein Length: 244
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purification: Affinity purification.
Product Form: Liquid
Formulation: Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: Ligand for the KLRK1/NKG2D receptor, together with at least ULBP2 and ULBP3. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to KLRK1/NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway. In CMV infected cells, interacts with soluble CMV glycoprotein UL16. The interaction with UL16 blocked the interaction with the KLRK1/NKG2D receptor, providing a mechanism by which CMV infected cells might escape the immune system. UL16 also causes ULBP1 to be retained in the ER and cis-Golgi apparatus so that it does not reach the cell surface.
Tissue Specificity: Expressed in T-cells, B-cells, erythroleukemia cell lines and in a wide range of tissues including heart, brain, lung, liver, testis, lymph node, thymus, tonsil and bone marrow. Also found in fetal heart, brain, lung and liver.
Sequence Similarities: Belongs to the MHC class I family.
Cellular Location: Cell membrane. Endoplasmic reticulum.

Detected intracellularly in the endoplasmic reticulum of CMV-infected fibroblasts.
UniProt: Q9BZM6
Gene ID: 80329
Synonyms: Alcan beta Antibody
ALCAN-beta Antibody
N2DL-1 Antibody
N2DL1 Antibody
N2DL1_HUMAN Antibody
NKG2D ligand 1 Antibody
NKG2D ligand 1 precursor Antibody
NKG2DL1 Antibody
RAET1I Antibody
Retinoic acid early transcript 1I Antibody
UL16 Antibody
UL16 binding protein 1 Antibody
UL16-binding protein 1 Antibody
Information: Target information shown above is from the UniProt Consortium.
Western blot analysis of extracts of Raji cells, using ULBP1 antibody.
Please Note: All batches are extensively validated and are guaranteed to work as specified, however, QC data is not necessarily from the current lot on sale.
Description: Rabbit polyclonal antibody to ULBP1
Application: IHC
Host: Rabbit
Reactivity: Human
Immunogen: Synthetic peptide of human UL16 binding protein 1

£234

Description: Rabbit Polyclonal Antibody to ULBP1
Application: ELISA, WB, IHC
Host: Rabbit
Isotype: IgG
Immunogen: UL16 binding protein 1

£284





Please Note: Anti-ULBP1 Antibody is for research use only. It is not intended for diagnostic or therapeutic use.
Antibodies.com | A10483
Size Price Quantity
50µl £148
100µl £243
200µl £372

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Lead Time: Currently 4-6 Days
Shipping Information
  • £20 to United Kingdom
  • £35 to Europe