Anti-WC1 Antibody [CC101] (A279997)

Anti-WC1 Antibody [CC101]

Mouse monoclonal [CC101] antibody to WC1.

This antibody recognises a subset of WC1+ T-cells expressing the WC1.1 isoform. The bovine WC1 cell surface antigen is expressed by a population of gamma/delta T-cells that lack CD2, CD4 and CD8, but express CD3. WC1 expression appears to be heterogeneous and antibodies to this cluster show differing reaction patterns. recognises the swine homolog of WC1, which is a 180 kDa molecule. In pigs, the 180 kDa molecule is expressed by a gamma/delta TCR positive T-cell population that also lack CD2, CD4 and CD8.

IP, Flow Cytometry, IHC-Fr

Use 10µl of the suggested working dilution to label 10⁶ cells in 100µl.

Bovine, Pig, Sheep

Con A stimulated bovine lymphocytes.

Mouse

Monoclonal

CC101

IgG2a

Unconjugated

Protein A affinity chromatography of tissue culture supernatant.

Liquid

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Mouse anti Bovine WC1 antibody, clone CC101, recognizes a subset of WC1+ T-cells expressing the WC1.1 isoform (MacHugh et al. 1993).The bovine WC1 cell surface antigen is expressed by a population of gamma/delta T-cells that lack CD2, CD4 and CD8, but express CD3. WC1 expression appears to be heterogeneous and antibodies to this cluster show differing reaction patterns (Crocker et al. 1993). Mouse anti bovine WC1, clone CC101, immunoprecipitates a 215 kDa molecule from bovine cells and also recognizes the swine homolog of WC1, which is a 180 kDa molecule. In pigs, the 180 kDa molecule is expressed by a gamma/delta TCR positive T-cell population that also lack CD2, CD4 and CD8 (Carr et al. 1994).

ATP7b, ATP7B_HUMAN, ATPase, Cu(2+) transporting, beta polypeptide, ATPase, Cu++ transporting, beta polypeptide, Copper pump 2, Copper transporting ATPase 2, PWD, Toxic milk, tx, WD, Wilson disease associated protein, Wilson disease-associated protein, WND, WND/140 kDa