Anti-WTAP Antibody [PCRP-BATF3-1E5] (A315794)

Anti-WTAP Antibody [PCRP-BATF3-1E5]

Mouse monoclonal [PCRP-BATF3-1E5] antibody to WTAP.

SNFT, also known as BATF3 (basic leucine zipper transcription factor, ATFlike 3), JUNDM1 or JDP1, is a 127 amino acid protein that localizes to the nucleus and contains one bZIP domain. Interacting with c-Jun, SNFT functions as a negative regulator of AP-1-mediated transcription, specifically by heterodimerizing with c-Jun and binding to DNA response elements. The gene encoding SNFT maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.

Flow Cytometry, IHC-P

Human tonsil. HeLa or HDLM-2 cells.

Flow Cytometry: 1-2 µg/million cells, IHC: 1-2 µg/ml

Human

Recombinant fragment (around Amino Acids 1-123) of human BATF3 protein (N-terminus).

Mouse

Monoclonal

PCRP-BATF3-1E5

IgG1

Unconjugated

Protein A/G chromatography.

200 µg/ml

14.47 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

DKFZp686F20131, Female-lethal(2)D homolog, FL2D_HUMAN, hFL(2)D, KIAA0105, MGC3925, Mum2, OTTHUMP00000017522, OTTHUMP00000017523, PNAS 132, PNAS-132, PNAS132, Pre mRNA splicing regulator WTAP, Pre-mRNA-splicing regulator WTAP, Putative pre mRNA splicing regulator female lethal 2D homolog, Putative pre mRNA splicing regulator female lethal(2D), Putative pre-mRNA splicing regulator female lethal(2D) homolog, putative pre-mRNA splicing regulator female-lethal(2D), Wilms tumor 1 associated protein, Wilms tumor 1 associating protein, Wilms tumor 1-associating protein, Wilms' tumor 1 associating protein, Wilms' tumour 1-associating protein, WT1 associated protein, WT1-associated protein, WT1-associating protein