Anti-ZBED1 Antibody [PCRP-ZBED1-1E1] (A250510)

Mouse monoclonal [PCRP-ZBED1-1E1] antibody to ZBED1 for Flow Cytometry, IF and WB.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-ZBED1 Antibody [PCRP-ZBED1-1E1]
Description
Mouse monoclonal [PCRP-ZBED1-1E1] antibody to ZBED1.
Specificity
ZBED1 (zinc finger BED domain-containing protein 1), also known as ALTE (Ac-like transposable element), DREF or TRAMP, is a 694 amino acid protein that localizes specifically to granular structures within the nucleus. Expressed ubiquitously at low levels and present at higher levels in heart, placenta, spleen and skeletal muscle, ZBED1 is thought to function as a transcription factor that regulates a number of ribosomal protein (RP) encoding genes, thereby playing a role in the cell cycle and in cell proliferation events. ZBED1 contains one BED-type zinc finger and binds specifically to 5 DNA regions found in RP promotors. Additionally, ZBED1 binds strongly to the promotor region of Histone H1 (a protein required for the condensation of nucleosomes into higher order structures), subsequently activating H1 transcription.
Applications
Flow Cytometry, IF, WB
Dilutions
Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, WB: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant full-length human ZBED1 protein.
Host
Mouse
Clonality
Monoclonal
Clone ID
PCRP-ZBED1-1E1
Isotype
IgG2a
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
86 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-ZBED1 Antibody [PCRP-ZBED1-1E1] - BSA and Azide free (A253690).
Synonyms
Ac like transposable element, ALTE, BED type zinc finger domain containing protein 1, DNA replication related element binding factor, DREF, dREF homolog, hDREF, KIAA0785, Putative Ac like transposon, Putative Ac-like transposable element, TRAMP, ZBED1_HUMAN, Zinc finger BED domain-containing protein 1, Zinc finger BED type containing 1
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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