Anti-ALDH1L1 Antibody [ALDH1L1/7702] - BSA and Azide free (A315826)

$765

Mouse monoclonal [ALDH1L1/7702] antibody to ALDH1L1 for WB and IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-ALDH1L1 Antibody [ALDH1L1/7702] - BSA and Azide free
Description
Mouse monoclonal [ALDH1L1/7702] antibody to ALDH1L1.
Specificity
Aldehyde dehydrogenases (ALDHs) mediate NADP+-dependent oxidation of aldehydes into acids during detoxification of alcohol-derived acetaldehyde, lipid peroxidation and metabolism of corticosteroids, biogenic amines and neurotransmitters. ALDH1L1 (aldehyde dehydrogenase 1 family member L1), also known as FTHFD or 10-FTHFD (10-formyltetrahydrofolate dehydrogenase), is a cytosolic protein that is developmentally regulated in the cerebellum. ALDH1L1 binds to folate and catalyzes the conversion of 10-formyltetrahydrofolate (10-FTHF) to tetrahydrofolate (THF). This suggests a possible role for ALDH1L1 in the regulation of cellular THF levels as well as in the inhibition of cell proliferation (as 10-FTHF is essential for the synthesis of purine). In addition, the overexpression of ALDH1L1 can restrict cell proliferation in vitro.
Applications
WB, IHC-P
Positive Control
Human kidney or liver. A549 or SK-BR3 cells.
Dilutions
WB: 1-2 µg/ml, IHC: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant fragment of human ALDH1L1 protein. The exact sequence is proprietary.
Host
Mouse
Clonality
Monoclonal
Clone ID
ALDH1L1/7702
Isotype
IgG
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Molecular Weight
99 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonyms
10 formyltetrahydrofolate dehydrogenase, 10 FTHFDH, 10-formyltetrahydrofolate dehydrogenase, 10-FTHFDH, AL1L1_HUMAN, Aldehyde dehydrogenase 1 family member L1, Aldehyde dehydrogenase family 1 member L1, Cytosolic 10-formyltetrahydrofolate dehydrogenase, DKFZp781N0997, EC 1.5.1.6, FDH, formyltetrahydrofolate dehydrogenase, FTHFD, OTTHUMP00000155221, OTTHUMP00000214696, OTTHUMP00000214700, OTTHUMP00000222724
Isotype Controls
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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