Recombinant Anti-Annexin A1 Antibody [ANXA1/6452R] (A277996)

Recombinant rabbit monoclonal [ANXA1/6452R] antibody to Annexin A1 for IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-Annexin A1 Antibody [ANXA1/6452R]
Description
Recombinant rabbit monoclonal [ANXA1/6452R] antibody to Annexin A1.
Specificity
The ANXA1 gene belongs to the annexin family, and contains 4 annexin repeats. A pair of annexin repeats may form one binding site for calcium and a phospholipid. ANXA1 promotes membrane fusion and is involved in exocytosis. The gene for ANXA1 is upregulated in hairy cell leukemia (HCL), and its protein expression is specific for HCL. Detection of ANXA1 provides a simple, highly sensitive and specific assay for diagnosing HCL. Annexin A1 has also been found to be protective against DNA damage induced by heat in breast cancer cells, suggesting it is involved in tumor suppressive and protective activities, and also is associated with treatment resistance.
Applications
IHC-P
Dilutions
IHC-P: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant full-length human Annexin A1 protein.
Host
Rabbit
Clonality
Monoclonal
Clone ID
ANXA1/6452R
Isotype
IgG
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
35 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-Annexin A1 Antibody [ANXA1/6452R] - BSA and Azide free (A278584).
Synonyms
Annexin 1, Annexin I, Annexin I (lipocortin I), Annexin-1, AnnexinA1, AnnexinI, ANX 1, ANX A1, ANX1, ANXA 1, ANXA1, ANXA1 protein, ANXA1_HUMAN, Calpactin 2, Calpactin II, Calpactin-2, CalpactinII, Chromobindin 9, Chromobindin-9, Chromobindin9, HGNC:533, Lipocortin 1, Lipocortin I, Lipocortin1, LipocortinI, LPC 1, LPC1, p35, Phospholipase A2 inhibitory protein
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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