Anti-ATF2 Antibody [PCRP-ATF2-1B4] - BSA and Azide free (A278153)

Mouse monoclonal [PCRP-ATF2-1B4] antibody to ATF2 for Flow Cytometry, IF, IP and WB.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-ATF2 Antibody [PCRP-ATF2-1B4] - BSA and Azide free
Description
Mouse monoclonal [PCRP-ATF2-1B4] antibody to ATF2.
Specificity
This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. The encoded protein may also be involved in cell's DNA damage response independent of its role in transcriptional regulation. Several alternatively spliced transcript variants have been found for this gene.
Applications
Flow Cytometry, IF, IP, WB
Dilutions
Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, IP: 1-2µg / 100-500µg proteins, WB: 1-2 µg/ml
Reactivity
Human
Cross Reactivity
This antibody is predicted to cross react with Mouse and Rat.
Immunogen
Recombinant full-length human ATF2 protein.
Host
Mouse
Clonality
Monoclonal
Clone ID
PCRP-ATF2-1B4
Isotype
IgG2b
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Molecular Weight
54.5 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-ATF2 Antibody [PCRP-ATF2-1B4] (A277565).
Synonyms
Activating transcription factor 2, Activating transcription factor 2 splice variant ATF2 var2, ATF 2, Atf-2, ATF2 protein, ATF2_HUMAN, cAMP Response Element Binding Protein 2, cAMP response element binding protein CRE BP1, cAMP response element-binding protein CRE-BP1, cAMP responsive element binding protein 2, formerly, cAMP-dependent transcription factor ATF-2, cAMP-responsive element-binding protein 2, CRE BP1, CRE-BP, CREB 2, CREB-2, CREB2, CREBP1, Cyclic AMP dependent transcription factor ATF 2, Cyclic AMP-dependent transcription factor ATF-2, Cyclic AMP-responsive element-binding protein 2, D130078H02Rik, D18875, HB 16, HB16, Histone acetyltransferase ATF2, MGC105211, MGC105222, MGC111558, MGC142504, mXBP, MXBP protein, Tg(Gzma-Klra1)7Wum, TREB 7, TREB7
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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