Anti-ATG5 Antibody [ATG5/2492] (A250661)

Anti-ATG5 Antibody [ATG5/2492]

Mouse monoclonal [ATG5/2492] antibody to ATG5.

The protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular processes, including autophagic vesicle formation, mitochondrial quality control after oxidative damage, negative regulation of the innate antiviral immune response, lymphocyte development and proliferation, MHC II antigen presentation, adipocyte differentiation, and apoptosis. The ATG5 protein is essential for autophagy; a process that is usually beneficial for cells to self-degrade their own components when they are no longer useful.

ELISA, WB, IHC-P

ELISA: 1-5 µg/ml, WB: 1-2 µg/ml, IHC-P: 1-2 µg/ml

Human

Recombinant fragment, around amino acids 1-119, of human ATG5 protein. The exact sequence is proprietary.

Mouse

Monoclonal

ATG5/2492

IgG1

kappa

Protein A/G chromatography.

200 µg/ml

50-32 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-ATG5 Antibody [ATG5/2492] - BSA and Azide free (A253841).

APG 5, APG 5L, APG5, APG5 autophagy 5 like, APG5 like, APG5-like, APG5L, APG5L/ATG5, Apoptosis specific protein, Apoptosis-specific protein, ASP, ATG 5, ATG5 autophagy related 5 homolog, ATG5_HUMAN, Autophagy protein 5, Autophagy related 5, hAPG5, Homolog of S Cerevisiae autophagy 5, OTTHUMP00000040507