Anti-C Reactive Protein Antibody (A282728)

Anti-C Reactive Protein Antibody

Goat polyclonal antibody to C Reactive Protein.

This antibody recognises human C-reactive protein (CRP), a calcium-binding acute phase reactant belonging to the pentraxin family which is secreted into the plasma by the liver, in response to cytokine stimulation.In addition to binding to phosphocholine residues, CRP can bind to other autologous and extrinsic ligands on targets, including damaged cell membranes, ribonucleoprotein particles, apoptotic cells and constituents of micro-organisms, and may activate the classical complement pathway through C1q recognition, making CRP a factor in a variety of host defense mechanisms. Levels of plasma CRP are significantly increased during the acute phase response, tissue injury and infection and can be used diagnostically as a marker of inflammation, disease progress and risk assessment of cardiovascular disease.

ELISA, Immunodiffusion

ELISA: 1:1,000, Immunodiffusion: 1:30 - 1:200

Human

Native human C-reactive protein.

Goat

Polyclonal

IgG

Unconjugated

Liquid

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Goat anti Human C-reactive protein antibody recognizes human C-reactive protein (CRP), a calcium-binding acute phase reactant belonging to the pentraxin family which is secreted into the plasma by the liver, in response to cytokine stimulation.In addition to binding to phosphocholine residues, CRP can bind to other autologous and extrinsic ligands on targets, including damaged cell membranes, ribonucleoprotein particles, apoptotic cells and constituents of micro-organisms, and may activate the classical complement pathway through C1q recognition, making CRP a factor in a variety of host defense mechanisms. Levels of plasma CRP are significantly increased during the acute phase response, tissue injury and infection and can be used diagnostically as a marker of inflammation, disease progress and risk assessment of cardiovascular disease.

C reactive protein pentraxin related, C-reactive protein(1-205), CRP, CRP_HUMAN, MGC88244, Pentraxin 1, Pentraxin 1, short, PTX 1, PTX1