This antibody recognises actin-like protein 6B.ACTL6B is is a member of a family of actin-related proteins (ARPs). ARPs are involved in a number of cellular processes, including chromatin remodelling, vesicular transport, and nuclear migration. ACTL6B is important for c-Myc oncogenic activity. ACTL6B is a subunit of the BAF (BRG1/brm-associated factor) complex in mammals, which is thought regulate expression of genes in brain tissue via structural remodelling of their chromatin. Rabbit anti Human ACT6B antibody detects a band of 50 kDa.
Applications
WB
Dilutions
WB: 1:250 - 1:500
Reactivity
Human
Immunogen
A peptide derived from within the N-terminus of human ACTL6B.
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Conjugate
Unconjugated
Concentration
Lot Specific
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline with 0.035% Sodium Azide and 30% Glycerol.
Storage
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.
General Notes
Rabbit anti Human ACTL6B antibody recognizes actin-like protein 6B.ACTL6B is is a member of a family of actin-related proteins (ARPs). ARPs are involved in a number of cellular processes, including chromatin remodelling, vesicular transport, and nuclear migration. ACTL6B is important for c-Myc oncogenic activity (Park et al. 2002). ACTL6B is a subunit of the BAF (BRG1/brm-associated factor) complex in mammals, which is thought regulate expression of genes in brain tissue via structural remodelling of their chromatin (Marcum et al. 2020).Rabbit anti Human ACT6B antibody detects a band of 50 kDa.
Synonyms
53 kDa BRG1-associated factor B, Actin-like protein 6B, Actin-related protein Baf53b, ACTL6, ACTL6B, ArpNalpha, BRG1-associated factor 53B
