Lyophilized from sterile Phosphate Buffered Saline, pH 7.4. Normally 5%–8% Trehalose is added as a protectant before lyophilization.
Storage
Shipped at 4°C. Lyophilized: Store at -20°C to -80°C. Reconstituted: Aliquot and store at -80°C. Product is stable for one year. Avoid freeze/thaw cycles.
General Notes
Prior to reconstitution, centrifuge the vial at 5,000g for 3-5 minutes at room temperature. Reconstitute with appropriate volume of distilled sterile water to bring product to 1mg/ml concentration. After addition of distilled sterile water, mix by gentle tapping. Note: It is not recommended to vortex or vigorously pipette the sample.
Synonyms
Activin receptor type IIB, Activin receptor type-2B, ACTR-IIB
ACVR2B expresion in Expi293 cells compared to irrelevant protein as analyzed by flow cytometry. Staining was performed with 15µg/ml of Bimagrumab Biosimilar - Anti-ACVR2B Antibody to obtain the blue histogram or the red histogram for the irrelevant protein.
ACVR2B expresion in Expi293 cells compared to irrelevant protein as analyzed by flow cytometry. Staining was performed with 1µg/ml of Bimagrumab Biosimilar - Anti-ACVR2B Antibody to obtain the blue histogram or the red histogram for the irrelevant protein.
Immobilised Recombinant Human ACVR2B Protein (C-terminal hFc Tag) (A332904) at 2 µg/ml (100 µl/well) can bind Bimagrumab Biosimilar - Anti-ACVR2B Antibody (A332183) in a linear range of 0.64–80 ng/ml. In order to specifically detect Bimagrumab Biosimilar - Anti-ACVR2B Antibody (A332183), mouse anti-human Fab-specific antibody was used as detection antibody.
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