Anti-BMP9 Antibody (A282725)

Anti-BMP9 Antibody

Rabbit polyclonal antibody to BMP9.

This antibody recognises human BMP9 (Bone Morphogenic Protein), a member of the TGF-beta superfamily.BMPs act through binding with a receptor complex consisting of type I and type II serine/threonine kinases, resulting ultimately in the activation of the Smad protein and mitogen-activated protein kinase (MAPK) signaling pathways. Several antagonist proteins, including, noggin, chordin, gremlin and follistatin, are responsible for modulating the signaling effects of BMPs, through the binding and blocking of receptor ligands, thereby preventing activation.

WB, IHC-P, ELISA, IF

ELISA: 1:2,000 - 1:20,000

Human

Synthetic peptide sequence CKDDMGVPTLKYH corresponding to amino acids 87 - 98 of the native molecule conjugated to Keyhole Limpet Haemocyanin.

CKDDMGVPTLKYH

Rabbit

Polyclonal

IgG

5 mg/ml

Liquid

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Rabbit anti Human BMP-9 antibody recognizes Human BMP9 (Bone Morphogenic Protein), a member of the TGF-beta superfamily.BMPs act through binding with a receptor complex consisting of type I and type II serine/threonine kinases, resulting ultimately in the activation of the Smad protein and mitogen-activated protein kinase (MAPK) signaling pathways. Several antagonist proteins, including, noggin, chordin, gremlin and follistatin, are responsible for modulating the signaling effects of BMPs, through the binding and blocking of receptor ligands, thereby preventing activation.

BMP-9, Bone morphogenetic protein 9, GDF-2, GDF2, Growth/differentiation factor 2