Anti-CD16 Antibody [3G8] - Low endotoxin, Azide free (A85705)

Anti-CD16 Antibody [3G8] - Low endotoxin, Azide free

Mouse monoclonal [3G8] antibody to CD16.

This antibody recognizes an extracellular epitope of CD16, a low affinity receptor for aggregated IgG (FcgammaRIII antigen). CD16 exists in two different isoforms: CD16a (FcgammaRIIIA, 50-65 kDa, expressed on NK-cells, monocytes, and macrophages) and CD16b (FcgammaRIIIB, 48 kDa, mainly expressed on neutrophils).

Flow Cytometry, IP, IHC-Fr, Functional Studies

FUNC: In vitro stimulation of NK cell proliferation, blocking of IgG binding and phagocytosis, inhibition of cytotoxic activity, in vivo NK cell depletion, Flow Cytometry: 6 µg/ml, IHC-Fr: Acetone fixation.

Human, Non-Human Primates

Human neutrophils.

Mouse

Monoclonal

3G8

IgG1

kappa

Protein A chromatography.

1 mg/ml

50-65 kDa

Liquid

Supplied in Phosphate Buffered Saline, pH 7.4, without Sodium Azide (0.2 µm filter sterilized). Endotoxin level is less than 0.01 EU/µg of the protein.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze/thaw cycles.

CD16-II, CD16a, CD16a antigen, Fc-gamma RIII, Fc-gamma RIII-alpha, Fc-gamma RIIIa, FCG3, FcgammaRIIIA, FCGR3, FCGR3A, FcR-10, FcRIII, FcRIIIa, IGFR3, IgG Fc receptor III-2, IgG Fc receptor III-A, Low affinity immunoglobulin gamma Fc region receptor III-A