Anti-CD205 Antibody [HD30] (A280583)

Anti-CD205 Antibody [HD30]

Mouse anti Human CD205

Mouse anti Human CD205 antibody, clone HD30 recognizes human Lymphocyte antigen 75, otherwise known as CD205, DEC205, C-type lectin domain family 13 member B or gp200-MR6. CD205 is a 1695 amino acid ~205 kDa single pass type I transmembrane glycoprotein and member of the macrophage mannose receptor family of C-type lectins, predominantly expressed by human dendritic cells.CD205 is a recycled endocytic receptor involved in directing antigen uptake for processing and presentation by MHC class I. Multiple isoforms of human CD205, generated by alternative splicing have been described. Mouse anti Human CD205 antibody, clone HD30 recognizes the canonical isoform 4, reactivity with other isoforms has not been evaluated but both isoforms 2 and 3 contain most of the immunogen sequence used to generate clone HD30 making reactivity likely. However the antibody is not expected to be reactive with isoforms 1 and 5 which lack the immunogen sequence (UniProt : 060449).

WB, Flow Cytometry, IHC-Fr

Human, Monkey

Purified extracellular domain of human CD205-IgG1 Fc fusion protein.

Mouse

Monoclonal

HD30

Protein G chromatography.

1 mg/ml

Liquid

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide and 1% BSA.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

C-type lectin domain family 13 member B, CLEC13B, gp200-MR6, Ly-75, LY75, Lymphocyte antigen 75