Anti-CD3 epsilon Antibody [APA1/1] (APC) (A121842)

Anti-CD3 epsilon Antibody [APA1/1] (APC)

Mouse monoclonal [APA1/1] antibody to CD3 epsilon (APC).

This antibody recognizes an activation-dependent intracellular epitope of CD3 epsilon. Exposure of the epitope precedes CD3 phosphorylation and the recruitment and activation of ZAP70, which initiates the signaling cascade produced by T-cell activation. This antibody provides the earliest known marker for TCR-mediated T cell activation.

Flow Cytometry: 1-2 µg/ml; Intracellular staining.

Mouse, Human

Human CD3 proteins isolated and purified from thymus.

Mouse

Monoclonal

IgG1

This antibody is conjugated with Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography; removing unconjugated antibody and free fluorochrome.

100 µg/ml

Liquid

Supplied in Phosphate Buffered Saline, pH 7.4, with 15 mM Sodium Azide.

Shipped at 4°C. Store in the dark at 2-8°C. Do not freeze!

CD3e, T-cell surface antigen T3/Leu-4 epsilon chain, T-cell surface glycoprotein CD3 epsilon chain, T3E

This product is for research use only. It is not intended for diagnostic or therapeutic use.