Specificity
Mouse anti Human CD44v4 antibody, clone VFF-11 recognizes an epitope encoded by exon v4 on the variant portion of human CD44. CD44v4 is strongly expressed on some breast cancer cell lines, notably epithelial-like BT-20 cells where v4 containing isoforms possess functional E-selectin ligand activity mediating cell adhesion under physiological flow conditions (Shirure et al. 2014).