Anti-CD45RC Antibody [3a56] (A279275)

Anti-CD45RC Antibody [3a56]

Mouse monoclonal [3a56] antibody to CD45RC.

This antibody recognises a restricted CD45 epitope encoded by the CD45 C exon and will detect the ~210 kDa RC isoform.CD45 in pigs has three cell surface expressed isoforms: CD45R, CD45RA, and CD45RC. CD45RC is mainly expressed by CD4+ T cells and weakly by B cells. However, during the immune response expression of CD45RC was found to decrease in activated T-helper cells. In contrast, increased expression of CD45RC was observed during the maturation of CD4- gamma delta thymocytes.

Flow Cytometry: Neat - 1:100, Use 10µl of the suggested working dilution to label 10⁶ cells in 100µl

Porcine

Mouse

Monoclonal

3a56

IgG1

1 mg/ml

Liquid

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Mouse anti Pig CD45RC, clone 3a56 recognizes a restricted CD45 epitope encoded by the CD45 C exon and will detect the ~210 kDa RC isoform.CD45 in pigs has three cell surface expressed isoforms: CD45R, CD45RA, and CD45RC (Schnitzlein and Zuckermann 1998). CD45RC is mainly expressed by CD4+ T cells and weakly by B cells (Piriou-Guzylack and Salmon 2008). However, during the immune response expression of CD45RC was found to decrease in activated T-helper cells (Saalmuller et al. 2002). In contrast, increased expression of CD45RC was observed during the maturation of CD4- gamma delta thymocytes (Sinkora et al. 2005).