Anti-CD52 Antibody [K263.3D7] (A280794)

Anti-CD52 Antibody [K263.3D7]

Mouse monoclonal [K263.3D7] antibody to CD52.

This antibody recognises porcine SWC1a, originally assigned at the 1st International Swine Cluster of Differentiation (CD) Workshop. SWC1a (CD52) is a cell surface molecule which is expressed by most leucocytes including resting T cells, monocytes and granulocytes. SWC1a is not expressed by the majority of B cells, erythrocytes or platelets. SWC1a, expressed at very much higher levels on monocytes than on mature macrophages, can be used with SWC9, expressed exclusively on mature tissue macrophages, to study intermediate stages of monocyte-macrophage differentiation.

Use 10µl of the suggested working dilution to label 1x10⁶ cells in 100µl

Porcine

Porcine peripheral blood Mononuclear cells.

Mouse

Monoclonal

K263.3D7

IgG1

1 mg/ml

Liquid

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Mouse anti Pig CD52, clone K263.3D7 is a monoclonal antibody recognizing porcine SWC1a, originally assigned at the 1st International Swine Cluster of Differentiation (CD) Workshop. SWC1a (CD52) is a cell surface molecule which is expressed by most leucocytes including resting T cells, monocytes and granulocytes. SWC1a is not expressed by the majority of B cells, erythrocytes or platelets (Leitner et al. 2012). SWC1a, expressed at very much higher levels on monocytes than on mature macrophages, can be used with SWC9, expressed exclusively on mature tissue macrophages, to study intermediate stages of monocyte-macrophage differentiation (Sanchez et al. 1999).

Cambridge pathology 1 antigen, CAMPATH-1 antigen, CDW52, Epididymal secretory protein E5, He5, Human epididymis-specific protein 5