Recombinant Anti-CD99 Antibody [MIC2/1495R] (A249334)

Anti-CD99 Antibody [MIC2/1495R]

Recombinant rabbit monoclonal [MIC2/1495R] antibody to CD99.

This antibody recognizes a sialoglycoprotein of 27-32kDa, identified as CD99, or MIC2 gene product, or E2 antigen. MIC2 gene is located in the pseudo-autosomal region of the human X and Y chromosome. MIC2 gene encodes two distinct proteins, which are produced by alternative splicing of the CD99 gene transcript and are identified as bands of 30 and 32kDa (p30/32).Although its function is not fully understood, CD99 is implicated in various cellular processes including homotypic aggregation of T cells, upregulation of T cell receptor and MHS molecules, apoptosis of immature thymocytes and leukocyte diapedesis.CD99 is expressed on the cell membrane of some lymphocytes, cortical thymocytes, and granulosa cells of the ovary. Most pancreatic islet cells, Sertoli cells of the testis, and some endothelial cells express this antigen. Mature granulocytes express very little or no CD99. MIC2 is strongly expressed on Ewings sarcoma cells and primitive peripheral neuroectodermal tumors.

IHC-P: 5-10 µg/ml

Human

Recombinant human MIC2 protein.

Rabbit

Monoclonal

MIC2/1495R

IgG

Protein A chromatography.

200 µg/ml

27-32 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-CD99 Antibody [MIC2/1495R] - BSA and Azide free (A252514).

12E7, CD99 antigen, E2 antigen, MIC2, MIC2X, MIC2Y, Protein MIC2, T-cell surface glycoprotein E2