General Notes
Rat anti Mouse CHD5 antibody, clone 5A10 recognizes chromodomain-helicase-DNA-binding protein 5, also known as ATP-dependent helicase CHD5.CHD5 is a 223 kDa member of the chromodomain helicase DNA-binding protein family of ATP-dependent chromatin remodeling complexes. Members of this family are characterized by a chromodomain, a helicase ATP-binding domain and an additional functional domain. CHD5 is a neuron-specific protein that is thought to play a role in chromatin remodeling and gene transcription (Li et al. 2014). CHD5 may also act as a tumor suppressor (Fatemi et al. 2014).Rat anti Mouse CHD5 antibody, clone 5A10 detects a band of 260 kDa.