Anti-CTBP2 Antibody (A320106)

Anti-CTBP2 Antibody

Rabbit polyclonal antibody to CTBP2.

This antibody recognises C-terminal-binding protein 2.CtBP2 is a protein that in humans is encoded by the CtBP2 gene. In mammals, C-terminal binding proteins (CtBP1 and CtBP2) function as transcriptional corepressors. CtBPs bind to many different DNA-binding proteins as well as other co-repressors, such as friend of GATA (Fog), that are themselves bound to DNA-binding proteins. CtBPs are also able to dimerize and multimerize to bridge larger transcriptional complexes and function as scaffold proteins that enable the assembly of gene repression complexes. In mammals, there are two distinct isoforms of CtBP2; a 56 kDa isoform that functions as a transcriptional repressor, and a 106 kDa isoform that is a major component of specialized synapses known as synaptic ribbons.recognises both isoforms 1 and 2 of CtBP2.

ChIP, WB

ChIP: 10 µl per ChIP, WB: 1:500 - 1:1,000

Human, Mouse

A peptide derived from the C-terminus of human CtBP2.

Rabbit

Polyclonal

IgG

Liquid

Supplied in Phosphate Buffered Saline with 0.035% Sodium Azide and 30% Glycerol.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Rabbit anti Human CtBP2 antibody recognizes C-terminal-binding protein 2.CtBP2 is a protein that in humans is encoded by the CtBP2 gene (Turner and Crossley, 2001). In mammals, C-terminal binding proteins (CtBP1and CtBP2) function as transcriptionalcorepressors (Shi et al. 2004). CtBPs bind to many different DNA-binding proteins as well as other co-repressors, such as friend of GATA (Fog), that are themselves bound to DNA-binding proteins (Fox et al. 1999).CtBPs are also able to dimerize and multimerize to bridge larger transcriptional complexes and function as scaffold proteins that enable the assembly of gene repression complexes. In mammals, there are two distinct isoforms of CtBP2; a 56 kDa isoform that functions as a transcriptional repressor, and a 106 kDa isoform that is a major component of specialized synapses known assynaptic ribbons.Rabbit anti human CtBP2 antibody recognizes both isoforms 1 and 2 of CtBP2.

C-terminal-binding protein 2