Recombinant Anti-Cystatin A Antibody [rCSTA/8995] (A314834)

Anti-Cystatin A Antibody [rCSTA/8995]

Recombinant mouse monoclonal [rCSTA/8995] antibody to Cystatin A.

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins, and kininogens. This gene encodes a stefin that functions as a cysteine protease inhibitor, forming tight complexes with papain and the cathepsins B, H, and L. The protein is one of the precursor proteins of cornified cell envelope in keratinocytes and plays a role in epidermal development and maintenance. Stefins have been proposed as prognostic and diagnostic tools for cancer.

THP-1 cells. Human tonsil or prostate tissue (IHC).

IHC: 1-2 µg/ml

Human

Recombinant fragment of human CSTA protein (around Amino Acids 1-98). The exact sequence is proprietary.

Mouse

Monoclonal

rCSTA/8995

kappa

Protein A/G chromatography.

200 µg/ml

11 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

CSTA, Cystatin-A, Cystatin-AS, Stefin-A, STF1, STFA