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Specifications
Name
Anti-Growth Hormone Antibody [GH/8136R] - BSA and Azide free
Description
Recombinant rabbit monoclonal [GH/8136R] antibody to Growth Hormone.
Specificity
Pituitary growth hormone (GH) plays a crucial role in stimulating and controlling the growth, metabolism and differentiation of many mammalian cell types by modulating the synthesis of multiple mRNA species. These effects are mediated by the binding of GH to its membrane-bound receptor, GHR, and involve a phosphorylation cascade that results in the modulation of numerous signaling pathways. GH is synthesized by acidophilic or somatotropic cells of the anterior pituitary gland. Anti-GH is a useful marker in classification of pituitary tumors and the study of pituitary disease (acromegaly).
Applications
IHC-P
Positive Control
Pituitary cells. Human pituitary tissue (IHC).
Dilutions
IHC: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant full-length human GH1 protein.
Host
Rabbit
Clonality
Monoclonal
Clone ID
GH/8136R
Isotype
IgG
Light Chains
kappa
Conjugate
Unconjugated
Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Molecular Weight
20 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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