Anti-HLA DP Antibody [SPM421] (A248839)

Anti-HLA DP Antibody [SPM421]

Mouse monoclonal [SPM421] antibody to HLA DP.

This antibody recognizes a non-polymorphic determinant of DP-MHC class II. MHC class II antigens are transmembrane glycoproteins of non-covalently linked alpha (33-35kDa) and beta (27-30kDa) chains. It reportedly reacts with B- non-T, non-B cell lines but not with T- and myeloid cell lines and leukemias. Differential expression of MHC class II antigens on fetal and adult lymphocytes, malignant B cells appears to reflect the stage of cell differentiation which may be useful in the study of lymphoproliferative disorders.

ELISA, Flow Cytometry, IF

Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml

Human

Non-T, non-B human acute lymphoblastic leukemia REH6 cell line.

Mouse

Monoclonal

SPM421

IgG2b

Protein A/G chromatography.

200 µg/ml

33-35 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-HLA DP Antibody [SPM421] - BSA and Azide free (A252019).