Anti-HLA DP Antibody [SPM421] - BSA and Azide free
Description
Mouse monoclonal [SPM421] antibody to HLA DP.
Specificity
This antibody recognizes a non-polymorphic determinant of DP-MHC class II. MHC class II antigens are transmembrane glycoproteins of non-covalently linked alpha (33-35kDa) and beta (27-30kDa) chains. It reportedly reacts with B- non-T, non-B cell lines but not with T- and myeloid cell lines and leukemias. Differential expression of MHC class II antigens on fetal and adult lymphocytes, malignant B cells appears to reflect the stage of cell differentiation which may be useful in the study of lymphoproliferative disorders.
Flow cytometric analysis of human Raji cells using Anti-HLA DP Antibody [SPM421] followed by Goat Anti-Mouse IgG (CF® 488) (Blue). Isotype Control (Red).
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