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Anti-IL-10 Antibody - BSA and Azide free (A282937)

This product is discontinued

Anti-IL-10 Antibody - BSA and Azide free (A282937) has been discontinued and is no longer available.

View all IL-10 Antibodies.

Name
Anti-IL-10 Antibody - BSA and Azide free
Description
Rabbit polyclonal antibody to IL-10.
Specificity
This antibody recognises mouse Interleukin-10 (IL-10), an immunosuppressive cytokine originally isolated from T helper type 2 cells (Th2), which is also secreted by B lymphocytes, macrophages, monocytes and keratinocytes.IL-10 inhibits the synthesis of several cytokines including Tumour Necrosis Factor, Interferon-gamma and Interleukin-2 and -3, and has a wide range of biological properties, including inhibition of the macrophage and Th cell-mediated cytokine synthesis suppression of the delayed hypersensitivity response. IL-10 may initially be involved in the polarization of Th2 responses.
Applications
WB, ELISA, Functional Assays
Dilutions
ELISA: 0.5 - 2 µg/ml, Functional Assays: 0.02 - 0.04 µg/ml, WB: 0.1 - 0.2 µg/ml
Reactivity
Mouse
Immunogen
Recombinant mouse IL-10.
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Conjugate

Unconjugated

Concentration
1 mg/ml after reconstitution.
Product Form
Lyophilized
Reconstitution
Reconstitute with 0.1 ml of distilled water. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Gently mix after reconstitution. For long term storage the addition of 0.09% sodium azide is recommended. For functional studies do not add sodium azide
Formulation
Supplied in Phosphate Buffered Saline.
Storage
Lyophilized: Store at -20°C. Reconstituted: Store undiluted at -20°C, avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.
General Notes
Rabbit anti Mouse Interleukin-10 antibody recognizes mouse Interleukin-10 (IL-10), an immunosuppressive cytokine originally isolated from T helper type 2 cells (Th2), which is also secreted by B lymphocytes, macrophages, monocytes and keratinocytes.IL-10 inhibits the synthesis of several cytokines including Tumour Necrosis Factor, Interferon-gamma and Interleukin-2 and -3, and has a wide range of biological properties, including inhibition of the macrophage and Th cell-mediated cytokine synthesis suppression of the delayed hypersensitivity response. IL-10 may initially be involved in the polarization of Th2 responses.
Synonyms
CSIF, Cytokine synthesis inhibitory factor, IL10, Interleukin-10
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.

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99.9% Relevancy Score
99.9% Relevancy Score
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99.5% Relevancy Score
99.2% Relevancy Score
99.1% Relevancy Score
98.8% Relevancy Score
98.6% Relevancy Score
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