Anti-Macrophage + Granulocyte Antibody [BM-1] (A250885)

Anti-Macrophage + Granulocyte Antibody [BM-1]

Mouse monoclonal [BM-1] antibody to Macrophage + Granulocyte.

This antibody recognizes a 183 kDa protein with DNA-binding characteristics, which is identified as a myeloid specific antigen. It reacts with myeloid precursor cells and granulocytes in bone marrow. Its antigen appears to be restricted to M2 and M3 acute myelogenous leukemia (AML) subtypes. This antibody reacts with early precursor and mature forms of human myeloid cells. It is useful in the identification of myelogenous leukemias, distinguishing granulocytic sarcomas from lymphoid malignancies, and also in the study of differentiation and transformation of human myeloid cells. The biological function of this antigen is not clear, although it has been proposed that it may play a role in the differentiation of myeloid cells.

Flow Cytometry, IF, IHC-P

Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, IHC-P: 1-2 µg/ml

Human

Human peripheral blood mononuclear cells.

Mouse

Monoclonal

BM-1

IgG1

Protein A/G chromatography.

200 µg/ml

183 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-Macrophage + Granulocyte Antibody [BM-1] - BSA and Azide free (A254065).