This antibody recognises CD112, also known as Poliovirus Receptor Related 2, PRR2 or Nectin-2, a surface molecule originally reported to be homologous to CD155, the poliovirus receptor. PRR2 expression is restricted to the myelo-monocytic and megakaryocytic lineages. PRR2 expression has also been detected on haematopoeitic progenitors expressing CD34.
Applications
IP, Flow Cytometry, IHC-Fr
Dilutions
Flow Cytometry: 1:50 - 1:100, Use 10µl of the suggested working dilution to label 106 cells in 100µl
Reactivity
Human
Host
Mouse
Clonality
Monoclonal
Clone ID
R2-525
Isotype
IgG1
Conjugate
Unconjugated
Purification
Protein G affinity chromatography of tissue culture supernatant.
Concentration
1 mg/ml
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.
Storage
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.
General Notes
Mouse anti Human CD112 antibody, clone R2-525 recognizes CD112, also known as Poliovirus Receptor Related 2, PRR2 or Nectin-2, a surface molecule originally reported to be homologous to CD155, the poliovirus receptor (Lopez et al. 1998). PRR2 expression is restricted to the myelo-monocytic and megakaryocytic lineages. PRR2 expression has also been detected on haematopoeitic progenitors expressing CD34.