Anti-NME1 Antibody [CPTC-NME1-2] - BSA and Azide free (A252703)

Anti-NME1 Antibody [CPTC-NME1-2] - BSA and Azide free

Mouse monoclonal [CPTC-NME1-2] antibody to NME1.

The nm23 gene, a potential suppressor of metastasis, was originally identified by differential hybridization between two murine melanoma sub-lines, one with a high and the second with a low metastatic capacity. Highly metastatic sub-lines exhibit much lower levels of nm23 than less metastatic cells. Based on sequence analysis, nm23 appears highly related to nucleotide diphosphate kinases (NDP-K). In humans, NDP kinase A and B are identical to two isotypes of human nm23 homologs, namely nm23-H1 and H2, respectively. nm23-H2 is identical in sequence to PuF, a transcription factor that binds to nuclease hypersensitive elements at positions 142 to 115 of the human C-Myc promotor.

WB: 1-2 µg/ml

Human

Recombinant full-length human NME1 protein.

Mouse

Monoclonal

CPTC-NME1-2

IgG2a

kappa

Protein A/G chromatography.

1 mg/ml

23 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-NME1 Antibody [CPTC-NME1-2] (A249523).

GAAD, Granzyme A-activated DNase, Metastasis inhibition factor nm23, NDK A, NDP kinase A, NDPKA, NM23, NM23-H1, Nucleoside diphosphate kinase A, Tumor metastatic process-associated protein