Anti-P90RSK1 Antibody (A283701)

Anti-P90RSK1 Antibody

Rabbit anti P90RSK1

Rabbit anti P90RSK1 antibody recognizes recognizes ribosomal protein S6 kinase alpha-1, also known as p90S6K, MAPK-activated protein kinase 1a, MAPKAPK-1a and RSK-1. It belongs to the RSK (ribosomal S6 kinase) family of serine/threonine kinases (Fisher and Blenis 1996). It is a downstream effector of Ras/ERK signalling pathway (Casalvieri et al. 2017). It directly phosphorylates IkappaBbeta and activates NF-kappaB (Xu et al. 2006). It has been reported to phosphorylate CREB on Ser133 (Cho et al. 2011). RSK also promotes mTOR signaling and translation (Shahbazian et al. 2006). Expression and activity of RSK1 promotes tumor growth and survival (Casalvieri et al. 2017).

Human

A synthetic peptide corresponding to a sequence from amino acid 600 to the C-terminus of human P90RSK1.

Rabbit

Polyclonal

IgG

Affinity chromatography.

Liquid

Supplied in Phosphate Buffered Saline with 50% Glycerol and 0.02% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

90 kDa ribosomal protein S6 kinase 1, MAP kinase-activated protein kinase 1a, MAPK-activated protein kinase 1a, MAPKAP kinase 1a, MAPKAPK-1a, MAPKAPK1A, p90-RSK 1, p90S6K, Ribosomal protein S6 kinase alpha-1, Ribosomal S6 kinase 1, RPS6KA1, RSK-1, S6K-alpha-1