Anti-PAK1 (phospho Thr212) Antibody (A94422)
Immunostaining with anti-activated PAK3-P-Ser154 antibodies of frontal cortical sections from E14.5 transgenic embryos expressing dtTomato in MGE cells (Nkx2.1-cre, Ai9 mouse strain). PAK3-P-Ser154 antibodies strongly label tangentially oriented structures (F1,F2) in the iz and svz, where Tomato-positive MGE-derived cells migrate tangentially. Enlarged views of cortical progenitors located along the ventricle (G1-G3) show that PAK3-P-Ser154 antibodies label the ?-tubulin positive centrioles (G2,G3) and the cellular cortex (G1,G3) of a subset of progenitors. cx, cortex; hi, hippocampus; th, thalamus; vz, ventricular zone; svz, subventricular zone; iz, intermediate zone; sp, subplate; cp, cortical plate; mz, marginal zone. . Scale bars: A1, 200 ?m; B1,C1, 500??m; D, 200 ?m; E1, 100 ?m ; F1, 100 ?m, G3, 10 ?m.