This antibody recognizes an extracellular epitope of CD170, a transmembrane glycoprotein expressed strongly by neutrophils, macrophages activated during infections, monocytes, and dendritic cells. This antibody cross-reacts with SIGLEC14, whose first two Ig domains are almost identical to those of CD170.
Applications
Flow Cytometry, IP, IHC-Fr, ICC, ELISA
Dilutions
Flow Cytometry: 1-4 µg/ml, IHC: 5-10 µg/ml.
Reactivity
Human, Non-Human Primates
Immunogen
Fusion protein composed of human CD170 extracellular domain and Fc region of human IgG1.
Host
Mouse
Clonality
Monoclonal
Clone ID
1A5
Isotype
IgG1
Conjugate
Unconjugated
Purification
Protein A chromatography.
Concentration
1 mg/ml
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline, pH 7.4, with 15 mM Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze/thaw cycles.
Synonyms
CD170, CD33 antigen-like 2, CD33L2, OB-binding protein 2, OB-BP2, OBBP2, Obesity-binding protein 2, Sialic acid-binding Ig-like lectin 5, Siglec-5