Anti-ZC3H7A Antibody [PCRP-ZC3H7A-1D6] (A277636)

Anti-ZC3H7A Antibody [PCRP-ZC3H7A-1D6]

Mouse monoclonal [PCRP-ZC3H7A-1D6] antibody to ZC3H7A.

The zinc finger CCCH domain-containing protein 7A (ZC3H7A), also known as ZC3H7, HSPC055 or ZC3HDC7, is a 971 amino acid protein that contains a C3H1-type zinc finger domain, three C3H1-type zinc fingers and three TPR repeats. Belonging to the ZC3H12 family, ZC3H7A localizes to the nucleus. Existing as two alternatively spliced isoforms, ZC3H7A is encoded by a gene located on human chromosome 16p13.13. Chromosome 16 makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, though through the CREBBP gene which encodes a critical CREB binding protein. Signs of RubinsteinTaybi include mental retardation and predisposition to tumor growth and white blood cell neoplasias. Crohn s disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene.

ELISA, IP, Flow Cytometry, IF

IP: 1-2µg / 100-500µg proteins, Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml

Human

Recombinant full-length human ZC3H7A protein.

Mouse

Monoclonal

PCRP-ZC3H7A-1D6

IgG1

Protein A/G chromatography.

200 µg/ml

110 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-ZC3H7A Antibody [PCRP-ZC3H7A-1D6] - BSA and Azide free (A278224).

ZC3H7, ZC3HDC7, Zinc finger CCCH domain-containing protein 7A