Anti-CD11a Antibody [DF1524] (A249063)

Anti-CD11a Antibody [DF1524]

Mouse monoclonal [DF1524] antibody to CD11a.

This antibody recognizes a protein of 180kDa, identified as CD11a (Leucocyte Workshop IV; Code 1524). CD11a complex with the 2 subunit of the integrin family, CD18, to form the cell surface heterodimer, LFA-1 or CD11a /C18 (aLbL). LFA-1 is expressed on all leukocytes including lymphocytes, monocytes, and granulocytes. It is involved in leukocyte adhesion to its ligands including intercellular adhesion molecule-1 (ICAM-1 or CD54), ICAM-2 (CD102), ICAM-3 (CD50) and Telencephalin (TLN) and play a role in most immune/inflammatory responses. This MAb potently blocks LFA-1 dependent homotypic cell aggregation.

Flow Cytometry, IF, Functional Studies

Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml

Human

Human CD11a protein.

Mouse

Monoclonal

DF1524

IgG2b

kappa

Unconjugated

200 µg/ml

180 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-CD11a Antibody [DF1524] - BSA and Azide free (A252243).

Antigen CD11A, Antigen CD11A (p180), lymphocyte function associated antigen 1, alpha polypeptide, CD 11a, CD11 antigen-like family member A, CD11a antigen, Integrin Alpha L, Integrin alpha-L, Integrin gene promoter, Integrin, alpha L (antigen CD11A (p180), lymphocyte function associated antigen 1; alpha polypeptide), ITAL_HUMAN, Itgal, ITGAL protein, Leukocyte adhesion glycoprotein LFA 1 alpha chain, Leukocyte adhesion glycoprotein LFA-1 alpha chain, Leukocyte Adhesion Glycoprotein LFA1 Alpha Chain, Leukocyte function associated molecule 1 alpha chain, Leukocyte function-associated molecule 1 alpha chain, LFA 1, LFA 1 alpha, LFA 1 alpha (LFA1A), LFA 1A, LFA-1A, LFA1A, Ly15, Ly21, Lymphocyte function associated antigen 1, Lymphocyte Function Associated Antigen Type 1 alpha, Lymphocyte function associated antigen, type 1, alpha subunit, lymphocyte function-associated antigen 1, alpha polypeptide, p180