Anti-CD11b Antibody [ICRF44] - BSA and Azide free (A280695)

$800

Mouse monoclonal [ICRF44] antibody to CD11b for IHC-Fr, Flow Cytometry, IP and Functional Assays.

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Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
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Email
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Highlighted products for Anti-CD11b Antibody

Name
Anti-CD11b Antibody [ICRF44] - BSA and Azide free
Description
Mouse monoclonal [ICRF44] antibody to CD11b.
Specificity
This antibody recognises the human CD11b cell surface glycoprotein, a 165 kDa molecule also known as the alphaM integrin, MAC-1 and CR3. This molecule is expressed as a heterodimer in association with the beta 2 integrin, and is found upon monocytes, granulocytes, NK cells and some peripheral blood lymphocytes. Mouse anti Human CD11b antibody, clone ICRF44 has been reported to have various functional effects on monocytes, blocking adhesion and stimulating cytokine and chemokine release.
Applications
IHC-Fr, Flow Cytometry, IP, Functional Assays
Dilutions
Flow Cytometry: 1:10 - 1:100, IHC-Fr 1: 1:100 - 1:1,000, Use 10µl of the suggested working dilution to label 106 cells or 100µl whole blood
Reactivity
Human, Cynomolgus monkey, Baboon, Rhesus Monkey
Cross Reactivity
This antibody does not cross react with Cat
Immunogen
Rheumatoid synovial cells and human monocytes.
Host
Mouse
Clonality
Monoclonal
Clone ID
ICRF44
Isotype
IgG1
Conjugate

Unconjugated

Purification
Protein G affinity chromatography of tissue culture supernatant.
Concentration
1 mg/ml
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline.
Storage
Store undiluted at -20°C only. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use.
General Notes
Mouse anti Human CD11b antibody, clone ICRF44 recognizes the human CD11b cell surface glycoprotein, a 165 kDa molecule also known as the alphaM integrin, MAC-1 and CR3. This molecule is expressed as a heterodimer in association with the beta 2 integrin, and is found upon monocytes, granulocytes, NK cells and some peripheral blood lymphocytes.Mouse anti Human CD11b antibody, clone ICRF44 has been reported to have various functional effects on monocytes, blocking adhesion and stimulating cytokine and chemokine release.
Synonyms
antigen CD11b (p170), Antigen CD11b p170, CD11 antigen like family member B, CD11 antigen-like family member B, CD11b/CD18, CD49d, Cell surface glycoprotein MAC-1 subunit alpha, Complement component 3 receptor 3 subunit, Complement Component Receptor 3 Alpha, Complement receptor type 3, alpha subunit, CR 3 alpha chain, CR 3 alpha chain (CR3A), CR-3 alpha chain, CR3, CR3A, F730045J24Rik, Integrin Alpha M, Integrin alpha M chain, Integrin alpha-M, Integrin beta 2 alpha subunit, Integrin subunit alpha M, integrin, alpha M (complement component 3 receptor 3 subunit), ITAM_HUMAN, ITGAM, Leukocyte adhesion receptor MO1, Ly-40, MAC 1, Mac-1a, MAC1, Mac1, alpha subunit, MAC1A, Macrophage antigen alpha polypeptide, MGC117044, Mo1, alpha subunit, MO1A, Neutrophil adherence receptor, Neutrophil adherence receptor alpha M subunit, SLEB6
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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