Anti-CD28 Antibody [204.12] (A250632)

Mouse monoclonal [204.12] antibody to CD28 for Flow Cytometry and IF.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-CD28 Antibody [204.12]
Description
Mouse monoclonal [204.12] antibody to CD28.
Specificity
This antibody recognizes a glycoprotein of 44-88kDa, which is identified as CD28. It is the critical T-cell co-stimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its co-stimulation role, CD28 functions in preventing T-cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. CD28 is also expressed on human fetal NK cells and some NK cell lines, whereas on murine NK cells the CD28 expression is much broader.
Applications
Flow Cytometry, IF
Dilutions
Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml
Reactivity
Human, Porcine, Bovine, Sheep, Mouse
Immunogen
Stimulated human leucocytes.
Host
Mouse
Clonality
Monoclonal
Clone ID
204.12
Isotype
IgG2a
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
44 kDa (monomer) / 88 kDa (dimer)
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-CD28 Antibody [204.12] - BSA and Azide free (A253812).
Synonyms
CD 28, CD28 antigen, CD28 molecule, CD28_HUMAN, MGC138290, T cell antigen CD28, T cell specific surface glycoprotein, T cell specific surface glycoprotein CD28, T-cell-specific surface glycoprotein CD28, TP44
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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