Anti-CD28 Antibody [AV7] (A279720)

Anti-CD28 Antibody [AV7]

Mouse monoclonal [AV7] antibody to CD28.

This antibody recognises the chicken homologue of mammalian CD28, demonstrating 50% sequence identity and conservation of key functional sequence. In chickens CD28 is expressed by all thymocytes and T cells excluding most of those that are gamma/delta TCR positive. The co-stimulatory role of CD28 is important to T cell function in chickens. Mouse anti chicken CD28, clone AV7 has been demonstrated to recognise Turkey CD28.

Flow Cytometry, IP

Use 10µl of the suggested working dilution to label 1x10⁶ cells in 100µl.

Chicken, Turkey

Chicken Leucocytes.

Mouse

Monoclonal

AV7

IgG1

Unconjugated

500 µg/ml

Liquid

Supplied in Borate Buffered Saline with <0.1% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Mouse anti Chicken CD28, clone AV7 recognizes the chicken homologue of mammalian CD28, demonstrating 50% sequence identity and conservation of key functional sequence. In chickens CD28 is expressed by all thymocytes and T cells excluding most of those that are gamma/delta TCR positive (Koskela et al. 1998). The co-stimulatory role of CD28 is important to T cell function in chickens (Arstila et al. 1994).Mouse anti chicken CD28, clone AV7 has been demonstrated to recognise Turkey CD28 (Powell et al. 2009).

CD 28, CD28 antigen, CD28 molecule, CD28_HUMAN, MGC138290, T cell antigen CD28, T cell specific surface glycoprotein, T cell specific surface glycoprotein CD28, T-cell-specific surface glycoprotein CD28, TP44